E-ISSN 2146-8133
 

Case Report 


A case of neuroleptic malignant syndrome following cardiac surgery

Atsushi Tamura, Hiroko Nakata, Takamichi Yoshizaki, Sho Kusadokoro.

Abstract
Neuroleptic malignant syndrome (NMS) is rare but sometimes causes life-threatening conditions. We report the case of a 53-year-old male patient who developed NMS following cardiac surgery. He was diagnosed with schizophrenia and pre- scribed blonanserin, chlorpromazine, and biperiden. From postoperative day 3, hyperthermia, disturbed consciousness, and involuntary movement were observed. Subsequently, his serum creatine phosphokinase (CPK) levels increased. After NMS was suspected, chlorpromazine and biperiden were stopped. From postoperative day 7, intravenous administration of dant- rolene was initiated. Following this treatment, his serum CPK levels gradually decreased, and the other symptoms improved. The treatment of NMS remains controversial. There is no evidence that dantrolene is effective for treating NMS; however, it may be one of the important options for treating NMS. We present the case and discuss the diagnosis and management of NMS following cardiac surgery.

Key words: Neuroleptic malignant syndrome, cardiac surgery, dantrolene


 
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How to Cite this Article
Pubmed Style

Tamura A, Nakata H, Yoshizaki T, Kusadokoro S. A case of neuroleptic malignant syndrome following cardiac surgery. Arch Clin Exp Surg. 2017; 6(2): 117-119. doi:10.5455/aces.20151012124332


Web Style

Tamura A, Nakata H, Yoshizaki T, Kusadokoro S. A case of neuroleptic malignant syndrome following cardiac surgery. http://www.ejmaces.com/?mno=200625 [Access: May 26, 2018]. doi:10.5455/aces.20151012124332


AMA (American Medical Association) Style

Tamura A, Nakata H, Yoshizaki T, Kusadokoro S. A case of neuroleptic malignant syndrome following cardiac surgery. Arch Clin Exp Surg. 2017; 6(2): 117-119. doi:10.5455/aces.20151012124332



Vancouver/ICMJE Style

Tamura A, Nakata H, Yoshizaki T, Kusadokoro S. A case of neuroleptic malignant syndrome following cardiac surgery. Arch Clin Exp Surg. (2017), [cited May 26, 2018]; 6(2): 117-119. doi:10.5455/aces.20151012124332



Harvard Style

Tamura, A., Nakata, H., Yoshizaki, T. & Kusadokoro, S. (2017) A case of neuroleptic malignant syndrome following cardiac surgery. Arch Clin Exp Surg, 6 (2), 117-119. doi:10.5455/aces.20151012124332



Turabian Style

Tamura, Atsushi, Hiroko Nakata, Takamichi Yoshizaki, and Sho Kusadokoro. 2017. A case of neuroleptic malignant syndrome following cardiac surgery. Archives of Clinical and Experimental Surgery (ACES), 6 (2), 117-119. doi:10.5455/aces.20151012124332



Chicago Style

Tamura, Atsushi, Hiroko Nakata, Takamichi Yoshizaki, and Sho Kusadokoro. "A case of neuroleptic malignant syndrome following cardiac surgery." Archives of Clinical and Experimental Surgery (ACES) 6 (2017), 117-119. doi:10.5455/aces.20151012124332



MLA (The Modern Language Association) Style

Tamura, Atsushi, Hiroko Nakata, Takamichi Yoshizaki, and Sho Kusadokoro. "A case of neuroleptic malignant syndrome following cardiac surgery." Archives of Clinical and Experimental Surgery (ACES) 6.2 (2017), 117-119. Print. doi:10.5455/aces.20151012124332



APA (American Psychological Association) Style

Tamura, A., Nakata, H., Yoshizaki, T. & Kusadokoro, S. (2017) A case of neuroleptic malignant syndrome following cardiac surgery. Archives of Clinical and Experimental Surgery (ACES), 6 (2), 117-119. doi:10.5455/aces.20151012124332





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