E-ISSN 2146-8133
 

Original Research (Original Article) 


Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas

Panicker Thomas Bipin, Jose Binu.

Abstract
Background: Most studies have demonstrated that patients in whom renal cell carcinomas (RCC) are incidentally detected have a better prognosis than those with symptoms related to RCC. This study aimed to compare the differences in the clinico-pathological features of incidentally detected and symptomatic RCC.
Methods: A retrospective study was conducted in patients who underwent surgical treatment for suspected renal masses and pathologically proven RCC. Histopathological data was retrieved from the pathology database. Incidentally diagnosed RCC and symptomatic tumors were compared. Significance was calculated using Fisher’s exact test.
Results: Of the total 179 patients, 41 (22.9%) were incidentally detected and 138 (77.1%) were symptomatic. Incidentally detected tumors were smaller, on average being 3.63 cm, and diagnosed at earlier stage and lower grade when compared to symptomatic tumors. More aggressive histology, such as sarcomatoid variants, collecting duct tumors and high grade tumors were more often seen in the symptomatic group.
Conclusions: Incidentally detected RCC has significantly better pathological prognostic factors than the symptomatic group. Symptomatic tumors present at a significantly higher stage, grade and are more aggressive than incidental lesions, particularly at later stages.

Key words: Kidney, renal cell carcinoma, incidental findings, sarcomatoid


 
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How to Cite this Article
Pubmed Style

Bipin PT, Binu J. Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. Arch Clin Exp Surg. 2017; 6(1): 28-32. doi:10.5455/aces.20160305075524


Web Style

Bipin PT, Binu J. Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. http://www.ejmaces.com/?mno=210521 [Access: August 17, 2018]. doi:10.5455/aces.20160305075524


AMA (American Medical Association) Style

Bipin PT, Binu J. Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. Arch Clin Exp Surg. 2017; 6(1): 28-32. doi:10.5455/aces.20160305075524



Vancouver/ICMJE Style

Bipin PT, Binu J. Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. Arch Clin Exp Surg. (2017), [cited August 17, 2018]; 6(1): 28-32. doi:10.5455/aces.20160305075524



Harvard Style

Bipin, P. T. & Binu, J. (2017) Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. Arch Clin Exp Surg, 6 (1), 28-32. doi:10.5455/aces.20160305075524



Turabian Style

Bipin, Panicker Thomas, and Jose Binu. 2017. Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. Archives of Clinical and Experimental Surgery (ACES), 6 (1), 28-32. doi:10.5455/aces.20160305075524



Chicago Style

Bipin, Panicker Thomas, and Jose Binu. "Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas." Archives of Clinical and Experimental Surgery (ACES) 6 (2017), 28-32. doi:10.5455/aces.20160305075524



MLA (The Modern Language Association) Style

Bipin, Panicker Thomas, and Jose Binu. "Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas." Archives of Clinical and Experimental Surgery (ACES) 6.1 (2017), 28-32. Print. doi:10.5455/aces.20160305075524



APA (American Psychological Association) Style

Bipin, P. T. & Binu, J. (2017) Clinico-pathological features of incidentally detected and symptomatic renal cell carcinomas. Archives of Clinical and Experimental Surgery (ACES), 6 (1), 28-32. doi:10.5455/aces.20160305075524





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