E-ISSN 2146-8133
 

Original Research (Original Article) 


Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery

Seher Altinel, Ismail Aydin Erden, Banu Ayhan, Seda Banu Akinci, Fatma Saricaoglu, Ulku Aypar.

Abstract
Background and Aim: Severe pain and comfortlessness may be seen in patients after arthroscopic knee surgery despite various commonly administered analgesic methods, particularly based on local anesthetics. The aim of this study was to determine the effect of intraarticular levobupivacaine injected preoperatively on pain relief and time to first analgesic request during the postoperative period.
Material and Methods: 40 adult-patients, ASA I and II, undergoing elective arthroscopic surgery were included in the study. Patients in the levobupivacaine group received intra-articular levobupivacaine at 5mg/ml dosages and 20 ml total volume 30 min before the procedure. Patients in the control group received 20 ml of normal saline. Visual analogue scale (VAS) scores were assessed at the 1st, 2nd, 4th, 8th, 12th and 24th hour postoperatively. Time to first analgesic request and total analgesics used over the course of 24 hours after the surgery were recorded. All patients received continuous morphine infusion via patient controlled analgesia (PCA) devices postoperatively. Additionally, patients’ pain satisfaction scores were recorded.
Results: Lower VAS scores at the 1st, 2nd, 4th and 8th hours postoperatively - both at rest and during motion - were found in the levobupivacaine group compared to the normal saline group (p<0.001, p<0.001, p<0.001 and p<0.02 respectively). Time to first analgesic request was longer with the levobupivacaine group than the group with saline (22.50 vs 15.00 min, p<0.02). A significant difference was found in consumed total opioid doses (9.10 vs 31.75 mg, p<0.001). The number of analgesic demands using PCA were significantly different between groups (10.80 v.s. 36.1 times in 24 hours, p<0.001).
Conclusion: Preemptive analgesia using intraarticular levobupivacaine 5 mg/ml (20 ml total volume) provides better pain control-evaluated through VAS scoring, time to first analgesic request and opioid consumption - compared to saline in patients undergoing arthroscopic knee surgery.

Key words: Preemptive analgesia, arthroscopy, intra-articular injection, levobupivacaine


 
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How to Cite this Article
Pubmed Style

Altinel S, Erden IA, Ayhan B, Akinci SB, Saricaoglu F, Aypar U. Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. Arch Clin Exp Surg. 2017; 6(2): 91-95. doi:10.5455/aces.20160725022731


Web Style

Altinel S, Erden IA, Ayhan B, Akinci SB, Saricaoglu F, Aypar U. Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. http://www.ejmaces.com/?mno=221223 [Access: August 17, 2018]. doi:10.5455/aces.20160725022731


AMA (American Medical Association) Style

Altinel S, Erden IA, Ayhan B, Akinci SB, Saricaoglu F, Aypar U. Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. Arch Clin Exp Surg. 2017; 6(2): 91-95. doi:10.5455/aces.20160725022731



Vancouver/ICMJE Style

Altinel S, Erden IA, Ayhan B, Akinci SB, Saricaoglu F, Aypar U. Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. Arch Clin Exp Surg. (2017), [cited August 17, 2018]; 6(2): 91-95. doi:10.5455/aces.20160725022731



Harvard Style

Altinel, S., Erden, I. A., Ayhan, B., Akinci, S. B., Saricaoglu, F. & Aypar, U. (2017) Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. Arch Clin Exp Surg, 6 (2), 91-95. doi:10.5455/aces.20160725022731



Turabian Style

Altinel, Seher, Ismail Aydin Erden, Banu Ayhan, Seda Banu Akinci, Fatma Saricaoglu, and Ulku Aypar. 2017. Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. Archives of Clinical and Experimental Surgery (ACES), 6 (2), 91-95. doi:10.5455/aces.20160725022731



Chicago Style

Altinel, Seher, Ismail Aydin Erden, Banu Ayhan, Seda Banu Akinci, Fatma Saricaoglu, and Ulku Aypar. "Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery." Archives of Clinical and Experimental Surgery (ACES) 6 (2017), 91-95. doi:10.5455/aces.20160725022731



MLA (The Modern Language Association) Style

Altinel, Seher, Ismail Aydin Erden, Banu Ayhan, Seda Banu Akinci, Fatma Saricaoglu, and Ulku Aypar. "Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery." Archives of Clinical and Experimental Surgery (ACES) 6.2 (2017), 91-95. Print. doi:10.5455/aces.20160725022731



APA (American Psychological Association) Style

Altinel, S., Erden, I. A., Ayhan, B., Akinci, S. B., Saricaoglu, F. & Aypar, U. (2017) Effectiveness of preemptive intra-articular levobupivacaine on pain relief after arthroscopic knee surgery. Archives of Clinical and Experimental Surgery (ACES), 6 (2), 91-95. doi:10.5455/aces.20160725022731





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