E-ISSN 2146-8133
 

Original Research (Original Article) 


Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero.

Abstract
Background: The number of publications reporting the appearance of post-radiation secondary tumors has increased in parallel with the development of radiotherapy. However, little information is available about the presence of sarcomas associated with prostate radiotherapy.
Objective: To review cases of pelvic sarcoma associated with prostate radiotherapy in a tertiary hospital.
Methods: Following the criteria established by Cahan, 11 pelvic sarcoma patients with a history of radiotherapy treatment of prostatic adenocarcinoma between the years 2006 to 2016 were identified. A descriptive study was designed to review the characteristics of patients, tumors, therapy administered, and its effect on the outcome of the cancer.
Results: The average age of patients upon diagnosis was 72.27 years (60-79), with an average latency time of 6.27 years (4-9 years) between radiotherapy and diagnosis of sarcoma. The mean radiotherapy dose was 74Gy (70-78). The most common location of the sarcoma was regions II-III of the pelvic girdle (72%), followed by the pelvic cavity. The main histological type was undifferentiated pleomorphic sarcoma (54%); two patients presented metastases at the time of diagnosis. In total, 81.8% of patients were treated surgically with curative intent, and of these, seven received adjuvant chemotherapy. Mean follow-up was 14 months, with a two-year survival rate of 18.2%.
Conclusion: Given the poor prognosis of post-radiation pelvic sarcomas, efforts must be made to establish protocols for early diagnosis and to develop aggressive, standardized treatment guidelines.

Key words: Post-radiation, sarcoma, prostate adenocarcinoma


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Irene Isabel Lopez-Torres
Articles by Jose Antonio Calvo-Haro
Articles by Lydia Mediavilla-Santos
Articles by Ruben Perez-Mañanes
Articles by Miguel Cuervo-Dehesa
Articles by Javier Vaquero
on Google
on Google Scholar
Article Statistics
 Viewed: 484
Downloaded: 267
Cited: 0

How to Cite this Article
Pubmed Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. Arch Clin Exp Surg. 2018; 7(3): 94-99. doi:10.5455/aces.20170921120541


Web Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. http://www.ejmaces.com/?mno=277648 [Access: November 13, 2018]. doi:10.5455/aces.20170921120541


AMA (American Medical Association) Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. Arch Clin Exp Surg. 2018; 7(3): 94-99. doi:10.5455/aces.20170921120541



Vancouver/ICMJE Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. Arch Clin Exp Surg. (2018), [cited November 13, 2018]; 7(3): 94-99. doi:10.5455/aces.20170921120541



Harvard Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero (2018) Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. Arch Clin Exp Surg, 7 (3), 94-99. doi:10.5455/aces.20170921120541



Turabian Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. 2018. Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. Archives of Clinical and Experimental Surgery (ACES), 7 (3), 94-99. doi:10.5455/aces.20170921120541



Chicago Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. "Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma." Archives of Clinical and Experimental Surgery (ACES) 7 (2018), 94-99. doi:10.5455/aces.20170921120541



MLA (The Modern Language Association) Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero. "Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma." Archives of Clinical and Experimental Surgery (ACES) 7.3 (2018), 94-99. Print. doi:10.5455/aces.20170921120541



APA (American Psychological Association) Style

Irene Isabel Lopez-Torres, Jose Antonio Calvo-Haro, Lydia Mediavilla-Santos, Ruben Perez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero (2018) Post-radiation pelvic sarcomas after radiotherapy treatment of prostate adenocarcinoma. Archives of Clinical and Experimental Surgery (ACES), 7 (3), 94-99. doi:10.5455/aces.20170921120541





Most Viewed Articles
  • Hirudotherapy /Leech therapy: Applications and Indications in Surgery
    Swaid Abdullah, Latief M. Dar, Adil Rashid, Anita Tewari
    Arch Clin Exp Surg. 2012; 1(3): 172-180
    » Abstract & References » doi: 10.5455/aces.20120402072447

  • Role of Probiotics in Dental Caries and Periodontal Disease
    Amit Bhardwaj, Shalu V Bhardwaj
    Arch Clin Exp Surg. 2012; 1(1): 45-49
    » Abstract & References » doi: 10.5455/aces.20120212100645

  • Use of Polyethylene Fiber (Ribbond) in Pediatric Dentistry
    Eda Arat Maden, Ceyhan Altun
    Arch Clin Exp Surg. 2012; 1(2): 110-115
    » Abstract & References » doi: 10.5455/aces.20120416115640

  • Attenuated familial adenomatous polyposis presenting as an abdominal wall mass
    Marc Paul Jose Lopez, John Paul Senon Gonzalez, Manuel Francisco Tanada Roxas
    Arch Clin Exp Surg. 2017; 6(1): 53-55
    » Abstract » doi: 10.5455/aces.20150809085449

  • Role of Ultrasonography (“Honeycomb Sign”) in Early Detection of Dengue Hemorrhagic Fever
    Sudhir Sachar, Sunder Goyal, Saurabh Sachar
    Arch Clin Exp Surg. 2013; 2(1): 38-42
    » Abstract & References » doi: 10.5455/aces.20120828025157

  • Barium Enema in the Diagnosis of Hirschsprung’s Disease: A Comparison with Rectal Biopsy
    Mohammad Abbas, Arshad Rashid, Asim Rafiq Laharwal, Ajaz Ahmad Wani, Shabir Ahmad Dar, Manzoor Ahamad Chalkoo, Showkat Majeed Kakroo
    Arch Clin Exp Surg. 2013; 2(4): 224-228
    » Abstract & References » doi: 10.5455/aces.20120703031135

  • Long-Term Productive Cough Caused by Tracheal Bronchus
    Chih-Hao Chen, Shih-Yi Lee, Ho Chang, Tzu-Ti Hung
    Arch Clin Exp Surg. 2012; 1(2): 120-121
    » Abstract & References » doi: 10.5455/aces.20120311102403

  • A Review of the Prevention and Treatment of Hypertrophic Scars: Part I Clinical Aspects
    Huseyin Karagoz, Celalettin Sever, Yalcin Bayram, Cihan Sahin, Yalcin Kulahci, Ersin Ulkur
    Arch Clin Exp Surg. 2012; 1(4): 237-248
    » Abstract & References » doi: 10.5455/aces.20120218124923

  • Patient Selection in Plastic Surgery: Recognizing Body Dysmorphic Disorder
    Cihan Sahin, Onat Yilmaz, Yalcin Bayram, Huseyin Karagoz, Celalettin Sever, Yalcin Kulahci, Alpay Ates
    Arch Clin Exp Surg. 2013; 2(2): 109-115
    » Abstract & References » doi: 10.5455/aces.20120722123102

  • Day–Care Surgery for Pilonidal Sinus Using Sinotomy Technique and Fibrin Glue Injection
    Selim Sozen, Vedat Ozturk, Koray Das, Hasan Erdem, Suleyman Cetinkunar, Ilhan Bali
    Arch Clin Exp Surg. 2012; 1(3): 138-141
    » Abstract & References » doi: 10.5455/aces.20120625121721

  • Most Downloaded
  • Attenuated familial adenomatous polyposis presenting as an abdominal wall mass
    Marc Paul Jose Lopez, John Paul Senon Gonzalez, Manuel Francisco Tanada Roxas
    Arch Clin Exp Surg. 2017; 6(1): 53-55
    » Abstract » doi: 10.5455/aces.20150809085449

  • Role of Probiotics in Dental Caries and Periodontal Disease
    Amit Bhardwaj, Shalu V Bhardwaj
    Arch Clin Exp Surg. 2012; 1(1): 45-49
    » Abstract & References » doi: 10.5455/aces.20120212100645

  • Hirudotherapy /Leech therapy: Applications and Indications in Surgery
    Swaid Abdullah, Latief M. Dar, Adil Rashid, Anita Tewari
    Arch Clin Exp Surg. 2012; 1(3): 172-180
    » Abstract & References » doi: 10.5455/aces.20120402072447

  • Patient Selection in Plastic Surgery: Recognizing Body Dysmorphic Disorder
    Cihan Sahin, Onat Yilmaz, Yalcin Bayram, Huseyin Karagoz, Celalettin Sever, Yalcin Kulahci, Alpay Ates
    Arch Clin Exp Surg. 2013; 2(2): 109-115
    » Abstract & References » doi: 10.5455/aces.20120722123102

  • Use of Polyethylene Fiber (Ribbond) in Pediatric Dentistry
    Eda Arat Maden, Ceyhan Altun
    Arch Clin Exp Surg. 2012; 1(2): 110-115
    » Abstract & References » doi: 10.5455/aces.20120416115640

  • Principles of risk management in surgery departments
    Fatemeh Rezaei, Mohammad H Yarmohammadian, Masoud Ferdosi, Abbas Haghshenas
    Arch Clin Exp Surg. 2015; 4(3): 126-134
    » Abstract & References » doi: 10.5455/aces.20140925015830

  • A Study of Methods Used to Reduce Surgical Site Infections
    Stuart R. Walker, Tara Anderson
    Arch Clin Exp Surg. 2012; 1(1): 27-33
    » Abstract & References » doi: 10.5455/aces.20120213053645

  • Slow-Release Drug Deliver System with Polylactic Acid Hydrogels in Prevention of Tracheal Wall Fibroplasia
    Jinrang Li, Lili Peng, Jianjun Sun, Hongguang Guo, Kun Guo, Zuogang Li, Yao Tang, Xu Sun, Shuangqing Zhang
    Arch Clin Exp Surg. 2012; 1(1): 1-7
    » Abstract & References » doi: 10.5455/aces.20120220105531

  • Post-Traumatic Pancreatic Pseudocyst: Report of Two Cases with Review of Literature
    Sunder Goyal, Sudhir Sachar, Ram Kumar Verma, Snigdha Goyal
    Arch Clin Exp Surg. 2013; 2(4): 251-258
    » Abstract & References » doi: 10.5455/aces.20120524103614

  • Role of Ultrasonography (“Honeycomb Sign”) in Early Detection of Dengue Hemorrhagic Fever
    Sudhir Sachar, Sunder Goyal, Saurabh Sachar
    Arch Clin Exp Surg. 2013; 2(1): 38-42
    » Abstract & References » doi: 10.5455/aces.20120828025157

  • Most Cited Articles
  • Hirudotherapy /Leech therapy: Applications and Indications in Surgery
    Swaid Abdullah, Latief M. Dar, Adil Rashid, Anita Tewari
    Arch Clin Exp Surg. 2012; 1(3): 172-180
    » Abstract & References » doi: 10.5455/aces.20120402072447
    Cited : 8 times [Click to see citing articles]

  • Experimental Craniofacial Composite Tissue Allotransplantation (CCTA) Models in Rats
    Yalcin Kulahci, Yalcin Bayram, Huseyin Karagoz, Celalettin Sever, Cihan Sahin
    Arch Clin Exp Surg. 2012; 1(3): 181-187
    » Abstract & References » doi: 10.5455/aces.20120514010906
    Cited : 7 times [Click to see citing articles]

  • Thoracodorsal Artery Perforator Flap: Basic Surgical Determinants
    Celalettin Sever, Yalcin Bayram, Cihan Sahin
    Arch Clin Exp Surg. 2012; 1(4): 270-271
    » Abstract & References » doi: 10.5455/aces.20120506072849
    Cited : 6 times [Click to see citing articles]

  • Pre-expanded Supraclavicular Flap for Post-burn Neck Contractures
    Celalettin Sever, Cihan Sahin
    Arch Clin Exp Surg. 2012; 1(1): 61-62
    » Abstract & References » doi: 10.5455/aces.20120205090034
    Cited : 4 times [Click to see citing articles]

  • Day–Care Surgery for Pilonidal Sinus Using Sinotomy Technique and Fibrin Glue Injection
    Selim Sozen, Vedat Ozturk, Koray Das, Hasan Erdem, Suleyman Cetinkunar, Ilhan Bali
    Arch Clin Exp Surg. 2012; 1(3): 138-141
    » Abstract & References » doi: 10.5455/aces.20120625121721
    Cited : 4 times [Click to see citing articles]

  • The effect of Kristeller maneuver on maternal and neonatal outcome
    Gokhan Acmaz, Evrim Albayrak, Gokalp Oner, Murvet Baser, Gulsum Aykut, Gulender Tas Tekin, Gokmen Zararsiz, Iptisam Ipek Muderris
    Arch Clin Exp Surg. 2015; 4(1): 29-35
    » Abstract & References » doi: 10.5455/aces.20140328024258
    Cited : 4 times [Click to see citing articles]

  • What is the Most Appropriate Animal Model for Experimental Diabetic Neuropathy Studies ?
    Huseyin Karagoz, Mustafa Tansel Kendirli
    Arch Clin Exp Surg. 2012; 1(3): 199-200
    » Abstract & References » doi: 10.5455/aces.20120514012617
    Cited : 3 times [Click to see citing articles]

  • Anesthetic Burns – A Burn Injury Due to A Combination of Local Anaesthetic and Heat Pack
    Stuart Robert Walker
    Arch Clin Exp Surg. 2012; 1(2): 127-128
    » Abstract & References » doi: 10.5455/aces.20120206110836
    Cited : 3 times [Click to see citing articles]

  • A Review of the Prevention and Treatment of Hypertrophic Scars: Part I Clinical Aspects
    Huseyin Karagoz, Celalettin Sever, Yalcin Bayram, Cihan Sahin, Yalcin Kulahci, Ersin Ulkur
    Arch Clin Exp Surg. 2012; 1(4): 237-248
    » Abstract & References » doi: 10.5455/aces.20120218124923
    Cited : 3 times [Click to see citing articles]

  • A Review of the Prevention and Treatment of Hypertrophic Scars: Part II. Experimental Studies
    Huseyin Karagoz, Yalcin Bayram, Celalettin Sever, Cihan Sahin, Yalcin Kulahci, Ersin Ulkur
    Arch Clin Exp Surg. 2013; 2(1): 49-58
    » Abstract & References » doi: 10.5455/aces.20120218125115
    Cited : 3 times [Click to see citing articles]