Evaluation of the Association between Breast Imaging Reporting and Data System for Ultrasonography (BIRADS) and Histopathology in Patients of Lump nn Breast: An Observational Study
Background: Breast cancer is one of the leading causes of cancer amongst women in India. Secondary prevention comprising of triple test (clinical, radiological and non- excision biopsy) helps in early detection of breast cancers. A concordant triple test is 100% sensitive and 100% specific to detect the malignant lesions. Diagnostic and management dilemma arises when triple test is non-concordant especially when ultrasonography denotes lump as probably benign and clinical and non-excision biopsy as benign. These patients are in constant state of anxiety about possibility of malignancy. Standard protocol at present is either to follow up the lump at 6 months interval with ultrasonography for a period of 2 years or to excise the lump and confirm with histopathology. Present study is focussed on diagnostic accuracy and predictive value of the ultrasonography in similar scenario.
Methods: The study design is an observational cohort study conducted from January 2021 to September 2021 in MGM Medical College, Indore on patients presenting to outpatient unit of surgery department with lump in the breast. A total of 60 patients were included. The objective of our study was to compare the result of radiological BIRADS Score with that of histopathology and calculate sensitivity, specificity, positive and negative predictive value.
Results: The sensitivity of BIRADS in the diagnosis of carcinoma of breast was 91.67%, specificity was 88.89%, positive predictive value was 84.62%, negative predictive value was 94.12% and diagnostic accuracy is 90%.
Conclusion: There is 6% probability of a benign lump as per BIRADS score to be malignant and 15% chances of a radiological malignant lump to be benign.HTML PDF