Abstract

Mohamed Abdel Megied Abo El-Magd, Mohamed Adel El-Maraghy, Mohamed E.A. Abdelrahim, Khaled Refaat Abd El Meguid, Mohamed Hussein Meabed

The aim of the work was to assess the prevalence of cardiac anomalies in primary congenital hypothyroidism (PCH) patients. Fifty patients with PCH recruited after diagnosis by ultrasonography or
scintigraphy (64% Dysgenesis, 36% Dyshormonogenesis). The prevalence of cardiac anomalies was
18%, with renal anomalies being 8%. There was no significant difference in the longitudinal followup of growth and sexual maturation between a hypothyroid with and without anomalies. Statistically
significant difference was found with replacement therapy of both groups. Hence, echocardiography
should be done to screen this birth defect as soon as possible so as to prevent or delay the possible
complications.